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本帖產(chǎn)生 1 個(gè) 翻譯EPI ，點(diǎn)擊這里進(jìn)行查看

shu4455742

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專業(yè): 天然藥物化學(xué)

[求助] 求大神翻譯個(gè)摘要

Uncertainty of quantitative microbiological methods of pharmaceutical analysis
The total uncertainty of quantitative microbiological methods, used in pharmaceutical analysis, consists of several components. The analysis of the most important sources of the quantitative microbiological methods variability demonstrated no effect of culture media and plate-count techniques in the estimation of microbial count while the highly significant effect of other factors (type of microorganism, pharmaceutical product and individual reading and interpreting errors) was established. The most appropriate method of statistical analysis of such data was ANOVA which enabled not only the effect of individual factors to be estimated but also their interactions. Considering all the elements of uncertainty and combining them mathematically the combined relative uncertainty of the test results was estimated both for method of quantitative examination of non-sterile pharmaceuticals and microbial count technique without any product. These data did not exceed 35%, appropriated for a traditional plate count methods.

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1樓 2015-12-30 19:56:23

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shu4455742(fjtony163代發(fā)): 金幣+15, 代發(fā) 2016-03-16 17:47:44
fjtony163: 翻譯EPI+1, 代發(fā) 2016-03-16 17:47:49

藥物分析中定量微生物學(xué)方法的不確定性
用于藥物分析的定量微生物學(xué)方法總的不確定性來源于幾個(gè)方面。對(duì)定量微生物學(xué)方法變異性最主要來源的分析表明培養(yǎng)基和平板計(jì)數(shù)的方法對(duì)微生物數(shù)量的估算沒有影響，而確立了有極顯著影響的其它因素（微生物類型、藥物產(chǎn)品和個(gè)人讀數(shù)以及解釋的誤差）。對(duì)這類數(shù)據(jù)最恰當(dāng)?shù)慕y(tǒng)計(jì)學(xué)方法是方差分析，它不僅可以估計(jì)單個(gè)因素的效應(yīng)，也能分析因素間的相互作用。對(duì)所有不確定性因素加以考慮并用數(shù)學(xué)方法將它們聯(lián)合起來。對(duì)非消毒藥物的定量檢測(cè)和那些沒有任何結(jié)果的微生物計(jì)數(shù)方法同時(shí)進(jìn)行了測(cè)試結(jié)果的聯(lián)合相對(duì)不確定性評(píng)估。這類數(shù)據(jù)不超過35%，適合于傳統(tǒng)的平板計(jì)數(shù)法。

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2樓2015-12-31 00:52:52