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xiaolu0424木蟲 (正式寫手)
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[交流]
求助一段(約240字)漢譯英
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對(duì)熱心幫忙者均感謝金幣3個(gè)以上,我認(rèn)為翻譯質(zhì)量較好的蟲友感謝30個(gè)金幣。謝謝大家! 獨(dú)一味為傳統(tǒng)藏藥,其制劑主要用于用于多種外科手術(shù)后的刀口疼痛、出血,外傷骨折,筋骨扭傷。風(fēng)濕痹痛以及崩漏、痛經(jīng)、牙齦腫痛、出血等。(2005版藥典)。獨(dú)一味藥材及制劑以前質(zhì)量控制采用以木犀草素為指標(biāo),但木犀草素缺乏專屬性,現(xiàn)有資料表明獨(dú)一味止血的有效部位為環(huán)烯醚萜類化學(xué)物,8-O-乙酰山酯苷甲酯是環(huán)烯醚萜類化合物中含量較高的化合物之一,又由于該化合物具有較強(qiáng)的專屬性。2010版藥典把8-O-乙酰山酯苷甲酯作為質(zhì)量控制的指標(biāo)之一,為了論證其合理性和為臨床用藥提供參考,我們對(duì)其進(jìn)行了臨床前藥動(dòng)學(xué)研究。 |
木蟲 (小有名氣)
| Lamiophlomis rotata Kudo,a traditional Tibetan medicine, its pharmaceutical preparation is mainly used for treating pain and bleeding after a variety of surgical incisions, trauma fractures, bones, muscles hurt, rheumatism and paralysis, uterine bleeding, dysmenorrhea, gingival swelling, as well as bleeding. (Pharmacopoeia 2005 Edition). Previously, luteolin was used as an index in the quality control of Kudo medicinal materials and preparations, however, luteolin is of low specificity. The existing data indicates that the effective components of Kudo for haemostasis is iridoid terpene chemicals, while 8-O-acetyl ester Hill methylester is a compound of this series with higher levels of content, also with strong specificity. Just for this reason, Hill 8-O-acetyl ester methylester has been selected as an indicator of quality control in Pharmacopoeia 2010 Edition. In order to demonstrate legitimacy of this method and provide a reference for clinical medication, its pre-clinical pharmacokinetic study was carried out in this thesis. |
木蟲 (小有名氣)
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