 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 17 | 1/1 | 返回列表 |
| 查看: 5293 | 回復(fù): 16 | ||||||
| 【獎勵】 本帖被評價7次，作者qinfujun增加金幣 5.6 個 | ||||||
[資源]
【資源分享】研究計劃和歸國計劃，根據(jù)以往的一些蟲友的改編 已有2人參與
|
||||||
|
Advisor’s information Name:****** Organization: Northwestern University Academic position: ****** Professor E-mail: ******@northwestern.edu TEL: ****** Address: ******, Chicago, IL 60611 Research plan Background:A number of key transcription factors, including the Androgen Receptor, the Polycomb group protein EZH2, and the TMPRSS2:ERG gene fusions, have been related to epigenetic changes and implicated in prostate cancer. As transcriptional regulation, for instance those by EZH2, eventually leads to inheritable epigenetic changes and thus altered chromatin status. Epigenetic mechanisms may be fundamental to tumorigenesis. Based on lab’s previous work, we hypothesized that in aggressive tumors altered transcriptional controls and chromatin states lead to de-differentiation and a stem cell like cellular status. In our study we will reveal the link between transcriptional control and epigenetic changes including histone methylation, DNA methylation and the regulation of miRNAs. Therefore the proposed work seeks to find the mechanisms between epigenetic regulation and prostate cancer. We plan to do the following projects: Project 1: Cell Culture and In Vitro Overexpression, Inhibition and Function Assays. From November 2010 to February 2011, I will conduct experiments on: cell lines culture, expression vector construct, RNA analysis by RT-PCR. Project 2: Protein Interaction Assay, ChIP-Seq Assays and Bioinformatics Analysis. From March 2011 to August 2011, I will perform the Assays on: Protein interaction between target genes, Chromatin immunoprecipitation using the histone methylation antibody and sequence the DNA fragments, Search the binding site sequence by Bioinformatics analysis. Project 3: Paper Writing and Publication From September 2011 to October 2011, I will write my research paper and submit it to a high influence factor journal. Return plan Epigenetic regulation, as one of the most fascinating research fields, has appeared in US & Europe since 2000’s. Now this discipline has emerged as a new research frontier and received more and more attention in the world. However, in China, epigenetics has only received little attention compared to overseas. In many universities and institutes, few people concentrate on epigenetic regulation. So plenty of researchers will be needed to work on this discipline in the near future. With good expertise in epigenetic research including histone methylation and DNA methylation acquired in National Key Laboratory of Crop Genetic Improvement (Huazhong Agricultural University) in past seven years and a deeper insight into epigenetic regulation that will be acquired in Northwestern University, I am full of confidence that after the completion of my post-doctoral research program, I will be able to find a suitable academic position in some university or institute in littoral of China or my home province. With good training in U.S and profound knowledge in epigenetics, I am confident of myself that I will be more competitive and have a much better chance in China. In addition, I will share my research experience abroad with future colleagues in China. [ Last edited by lywang2008 on 2010-12-7 at 06:24 ] |
回復(fù)此樓» 收錄本帖的淘帖專輯推薦
 大慈大悲觀世音 | 美國J簽證經(jīng)驗 | 寶貴資料 | 花花要留學 |
» 猜你喜歡
08工學調(diào)劑
已經(jīng)有16人回復(fù)
-
0703化學調(diào)劑，求導(dǎo)師收
已經(jīng)有7人回復(fù)
-
0854AI CV方向招收調(diào)劑
已經(jīng)有3人回復(fù)
-
求調(diào)劑323材料與化工
已經(jīng)有3人回復(fù)
-
生物學學碩求調(diào)劑
已經(jīng)有9人回復(fù)
-
289求調(diào)劑
已經(jīng)有8人回復(fù)
-
07化學280分求調(diào)劑
已經(jīng)有5人回復(fù)
-
300分，材料，求調(diào)劑，英一數(shù)二
已經(jīng)有4人回復(fù)
-
【考研調(diào)劑】化學專業(yè) 281分，一志愿四川大學，誠心求調(diào)劑
已經(jīng)有16人回復(fù)
-
0854電子信息求調(diào)劑
已經(jīng)有7人回復(fù)
» 本主題相關(guān)價值貼推薦，對您同樣有幫助:
- 求問如何寫研究計劃？請大家指點迷津~交流經(jīng)驗~
已經(jīng)有14人回復(fù)
- 請教各位關(guān)于研究計劃的一些問題？在線等。。。
已經(jīng)有10人回復(fù)
- 怎樣的研究計劃才叫漂亮
已經(jīng)有17人回復(fù)
- 英國紐卡斯爾大學 獎學金申請、研究計劃問題！焦急求教��！
已經(jīng)有14人回復(fù)
- 參與的國家自然科學基金重大研究計劃培育項目算不算限項里面？
已經(jīng)有5人回復(fù)
- 【求助完結(jié)】請問，研究計劃，老板簽字之后掃描傳給我，可行嗎？
已經(jīng)有10人回復(fù)
- 【求助】懸賞！攻博需不需要在研究計劃里面寫回國計劃？
已經(jīng)有31人回復(fù)
- 【交流討論】公派攻博研究計劃
已經(jīng)有9人回復(fù)
- 【求助】請問聯(lián)培的蟲友們，有了研修計劃，還需要寫論文開題報告么
已經(jīng)有6人回復(fù)
- 浙江省2011年度省公益性技術(shù)應(yīng)用研究計劃項目開始申報
已經(jīng)有13人回復(fù)
- 填寫項目研究計劃書注意事項
已經(jīng)有75人回復(fù)
- 別為了小基金沒中發(fā)愁，這才是大蛋糕——重大研究計劃項目指南及申請注意事項
已經(jīng)有10人回復(fù)
- 【版內(nèi)資源】簽證指南直通車（各國簽證資源、經(jīng)驗分享匯總）
已經(jīng)有24人回復(fù)
2樓2010-10-30 21:26:28
3樓2010-10-30 23:35:28
4樓2010-10-31 17:20:28
5樓2010-11-01 09:46:03
6樓2010-11-01 10:12:57
7樓2010-12-06 16:03:17
8樓2010-12-07 01:46:00
9樓2010-12-09 08:28:46
10樓2010-12-10 00:06:54
11樓2011-06-24 16:11:45
13樓2011-08-06 10:08:07
15樓2013-05-06 21:03:24
16樓2013-05-06 22:30:10
17樓2013-11-22 20:51:20
簡單回復(fù)
greenlee12樓
2011-07-24 17:30
回復(fù)
五星好評 謝謝分享！
chengjiu14樓
2011-11-30 12:22
回復(fù)
五星好評 
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 qinfujun 的主題更新
| 17 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 0805 316求調(diào)劑 +4 | 大雪深藏 2026-03-18 | 4/200 |
|
|---|---|---|---|---|
|
|
[考研] 求調(diào)劑 +5 | 林之夕 2026-03-24 | 5/250 |
|
|
|
[考研] 070300化學求調(diào)劑 +9 | 苑豆豆 2026-03-20 | 9/450 |
|
|
|
[材料工程] 一志愿C9材料與化工專業(yè)總分300求調(diào)劑 +4 | 曼111 2026-03-24 | 5/250 |
|
|
|
[考研] 一志愿哈工大，085400，320，求調(diào)劑 +3 | gdlf9999 2026-03-24 | 3/150 |
|
|
[考研] 291求調(diào)劑 +8 | hhhhxn.. 2026-03-23 | 8/400 |
|
|
|
[考研] 284求調(diào)劑 +3 | yanzhixue111 2026-03-23 | 6/300 |
|
|
|
[考研] 0703化學求調(diào)劑 +4 | 奶油草莓. 2026-03-22 | 5/250 |
|
|
|
[考研] 333求調(diào)劑 +3 | ALULU4408 2026-03-23 | 3/150 |
|
|
|
[考研] 一志愿上海交大生物與醫(yī)藥專碩324分，求調(diào)劑 +5 | jiajunX 2026-03-22 | 5/250 |
|
|
|
[考研] 306求調(diào)劑 +9 | chuanzhu川燭 2026-03-18 | 9/450 |
|
|
|
[考研] 初試 317 +7 | 半拉月丙 2026-03-20 | 7/350 |
|
|
|
[考研] 化學調(diào)劑 +5 | yzysaa 2026-03-21 | 5/250 |
|
|
|
[考研] 材料求調(diào)劑 +5 | @taotao 2026-03-21 | 5/250 |
|
|
|
[考研] 求調(diào)劑 +4 | 要好好無聊 2026-03-21 | 4/200 |
|
|
|
[考研] 330求調(diào)劑0854 +3 | assdll 2026-03-21 | 3/150 |
|
|
|
[考研] 一志愿華中科技大學，080502，354分求調(diào)劑 +5 | 守候夕陽CF 2026-03-18 | 5/250 |
|
|
|
[考研] 材料學碩297已過四六級求調(diào)劑推薦 +11 | adaie 2026-03-19 | 11/550 |
|
|
|
[考研] 288求調(diào)劑，一志愿華南理工大學071005 +5 | ioodiiij 2026-03-17 | 5/250 |
|
|
|
[考研] 本科鄭州大學物理學院，一志愿華科070200學碩，346求調(diào)劑 +4 | 我不是一根蔥 2026-03-18 | 4/200 |
|