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906632716新蟲 (小有名氣)
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| 聚乙二醇在藥物合成上有很廣泛的用途，但其端羥基的活性相對較低，直接應(yīng)用受到限制，若把羥基活化為羧基則可以擴(kuò)大其應(yīng)用面，尤其在合成二聚物時，把疏水鏈換成親水的聚乙二醇二丁二酸脂鏈，以增加橋鏈的親水性。以聚乙二醇、丁二酸酐為反應(yīng)物，吡啶為溶劑，分別合成聚乙二醇二丁二酸酯。結(jié)果顯示：在反應(yīng)時間充足時反應(yīng)比較徹底。 |
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petrocatal
木蟲 (正式寫手)
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906632716(金幣+1): 2010-11-07 15:43:42
| The polyethylene glycol(PEG) are widespreadly applied to medicine synthesis snd yet the direct use is limited due to the low end activity of hydroxyl groups. The application of PEG could be extended with the conversion of the hydroxyls to the carboxyls. Especially when used in the synthesis of dipolymers, the hydrophilic chains were replaced by hydrophobic chains for increasing hydrophilic property of the brindge chains. Poly(diethylene Glycol Succinate) was synthesied with polyethylene glycol and succinic anhydride as reactants, and pyridine as the solvent. It was found that reactants could consumed conpletely with enough reaction time. |
4樓2010-11-06 05:05:23
906632716(金幣+5, 翻譯EPI+1): 2010-11-07 15:43:24
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The polyethylene glycol has the very widespread use in the medicine synthesis, but its end hydroxyl's activeness is relatively low, the direct application is restricted, if activates the hydroxyl for the carboxyl group may expand its application areas. Especially in the synthesis of dipolymers,the hydrophilic chain was changed into hydrophobic chain to ehanced the hydrophilic property. With polyethylene glycol and succinic anhydride for reactants,pyridine as the solvent ,the Poly(diethylene Glycol Succinate) was synthesized respecvtively.The results showed that the reaction was completely done if the reaction time was enough. Poly(diethylene Glycol Succinate) 聚二乙二醇丁二酸酯 網(wǎng)上查的都是這個名稱 如果你的名稱不是這個的話你自己修改一下 我的翻譯供你參考 |
2樓2010-11-05 20:30:54
petrocatal
木蟲 (正式寫手)
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906632716(金幣+4): 2010-11-07 15:43:37
| The polyethylene glycol(PEG) are widespreadly applied to medicine synthesis snd yet the direct use is limited due to the low end activity of hydroxyl groups. The application of PEG could be extended with the conversion of the hydroxyls to the carboxyls. Especially when used in the synthesis of dipolymers, the hydrophilic chains were replaced by hydrophobic chains for increasing hydrophilic property of the brindge chains. Poly(diethylene Glycol Succinate) was synthesied with polyethylene glycol and succinic anhydride as reactants, and pyridine as the solvent. The results showed that the with enough reaction. |
3樓2010-11-06 04:59:05
petrocatal
木蟲 (正式寫手)
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- 專業(yè): 有機(jī)化工
5樓2010-11-07 22:03:30
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