 |
 |
 |
 |
 |
 |
||
 |
 |
 |
 |
 |
| 5 | 1/1 | 返回列表 |
| 查看: 681 | 回復(fù): 3 | |||
| 當(dāng)前只顯示滿足指定條件的回帖，點擊這里查看本話題的所有回帖 | |||
325865959銅蟲 (初入文壇)
|
[求助]
請問有沒有模擬酶分子酸堿耐受性的算法，軟件，或者綜述？
|
||
|
見過模擬蛋白質(zhì)熱穩(wěn)定性的算法，但是有沒有模擬酶分子酸堿耐受性的算法呢？都是什么原理呀？一般工業(yè)酶改造需要用到提高酸堿耐受范圍，是隨機(jī)突變呢還是有理性設(shè)計的方法指導(dǎo)？ [ Last edited by 325865959 on 2013-5-24 at 11:22 ] |
回復(fù)此樓» 猜你喜歡
一志愿中南大學(xué)化學(xué)0703總分337求調(diào)劑
已經(jīng)有5人回復(fù)
-
394求調(diào)劑
已經(jīng)有5人回復(fù)
-
一志愿北京工業(yè)大學(xué)，324分求調(diào)劑
已經(jīng)有3人回復(fù)
-
一志愿廈門大學(xué)化學(xué)學(xué)碩307求調(diào)劑
已經(jīng)有10人回復(fù)
-
壓國家一區(qū)線，求導(dǎo)師收留，有恩必謝！
已經(jīng)有6人回復(fù)
-
化學(xué)0703 調(diào)劑 306分 一志愿211
已經(jīng)有3人回復(fù)
-
317分 一志愿南理工材料工程 本科湖工大 求調(diào)劑
已經(jīng)有6人回復(fù)
-
070305高分子化學(xué)與物理 304分求調(diào)劑
已經(jīng)有3人回復(fù)
-
求調(diào)劑
已經(jīng)有6人回復(fù)
-
329求調(diào)劑
已經(jīng)有6人回復(fù)
» 本主題相關(guān)商家推薦: (我也要在這里推廣)
325865959
銅蟲 (初入文壇)
- 應(yīng)助: 0 (幼兒園)
- 金幣: 145.3
- 帖子: 41
- 在線: 24.7小時
- 蟲號: 2344181
- 注冊: 2013-03-13
- 性別: MM
- 專業(yè): 微生物生理與生物化學(xué)
| PROPKA software: "The PROPKA Graphical User Interface (GUI) is a new tool for studying the pH-dependent properties of proteins such as charge and tabilization energy. It facilitates a quantitative analysis of pKa values of ionizable residues together with their structural determinants by providing a direct link between the pKa data, predicted by the PROPKA calculations, and the structure via the Visual Molecular Dynamics (VMD) program." |
3樓2013-05-27 12:55:56
325865959
銅蟲 (初入文壇)
- 應(yīng)助: 0 (幼兒園)
- 金幣: 145.3
- 帖子: 41
- 在線: 24.7小時
- 蟲號: 2344181
- 注冊: 2013-03-13
- 性別: MM
- 專業(yè): 微生物生理與生物化學(xué)
| pKD software: "The pKa values inproteins governthe pH-dependence of protein stability and enzymatic activity. A large number of mutagenesis experiments have been carried out in the last three decades to re-engineer the pH-activity and pH-stability profile of enzymes and proteins. We have developed the pKD webserver (http://polymerase.ucd.ie/pKa_Design), which predicts sets of point mutations that will change the pKa values of a set of target residues in a given direction, thus allowing for targeted re-design of the pH-dependent characteristics of proteins." |
2樓2013-05-27 12:50:53
1054950560
金蟲 (正式寫手)
- 應(yīng)助: 1 (幼兒園)
- 金幣: 1338.7
- 散金: 25
- 紅花: 7
- 帖子: 327
- 在線: 138.2小時
- 蟲號: 1658658
- 注冊: 2012-03-02
- 性別: GG
- 專業(yè): 藥物化學(xué)
4樓2013-05-27 16:31:18
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 化學(xué)0703 調(diào)劑 306分 一志愿211 +3 | 26要上岸 2026-03-28 | 3/150 |
|
|---|---|---|---|---|
|
|
[考研] 070305高分子化學(xué)與物理 304分求調(diào)劑 +3 | c297914 2026-03-28 | 3/150 |
|
|
|
[考研] 070300求調(diào)劑306分 +4 | 26要上岸 2026-03-27 | 4/200 |
|
|
|
[考研] 數(shù)一英一271專碩（085401）求調(diào)劑，可跨 +4 | 前行必有光 2026-03-28 | 5/250 |
|
|
|
[考研] 學(xué)碩274求調(diào)劑 +6 | Li李魚 2026-03-26 | 6/300 |
|
|
|
[考研] 求調(diào)劑推薦 材料 304 +15 | 荷包蛋hyj 2026-03-26 | 15/750 |
|
|
[考研] 275求調(diào)劑 +10 | jjjjjjjjjjl 2026-03-27 | 10/500 |
|
|
|
[考研] 275求調(diào)劑 +10 | Micky11223 2026-03-25 | 13/650 |
|
|
|
[有機(jī)交流]
高溫高壓反應(yīng)求助
 10+4
|
chibby 2026-03-25 | 4/200 |
|
|
|
[考研] 化學(xué)調(diào)劑 +4 | 愛吃番茄的旭 2026-03-24 | 5/250 |
|
|
|
[考研] 317求調(diào)劑 +7 | 蛋黃咸肉粽 2026-03-26 | 7/350 |
|
|
|
[考研] 085601求調(diào)劑總分293英一數(shù)二 +4 | 鋼鐵大炮 2026-03-24 | 4/200 |
|
|
|
[考研] 303求調(diào)劑 +6 | 藍(lán)山月 2026-03-25 | 6/300 |
|
|
|
[考研] 求b區(qū)院校調(diào)劑 +4 | 周56 2026-03-24 | 5/250 |
|
|
|
[考研] 各位老師您好：本人初試372分 +5 | jj涌77 2026-03-25 | 6/300 |
|
|
|
[考研] 0854電子信息求調(diào)劑 +7 | α____ 2026-03-22 | 9/450 |
|
|
|
[考研] 材料調(diào)劑 +3 | iwinso 2026-03-23 | 3/150 |
|
|
|
[考研] 一志愿北化315 求調(diào)劑 +3 | akrrain 2026-03-24 | 3/150 |
|
|
|
[考研] 求老師收我 +3 | zzh16938784 2026-03-23 | 3/150 |
|
|
|
[考研] 293求調(diào)劑 +3 | 濤濤Wjt 2026-03-22 | 5/250 |
|