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[求助]
求翻譯一段醫(yī)學(xué)方面的英文文獻(xiàn)
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Chemotherapy after study discontinuation was admin-istered to 64% of patients randomly assigned to docetaxel and 70% of patients randomly assigned to paclitaxel. Among the patients randomly assigned to docetaxel, 20% were later treated with paclitaxel, whereas 19% of patients randomly assigned to paclitaxel received docetaxel as sal-vage therapy. Thirteen percent of docetaxel patients and 17% of paclitaxel patients were re-treated with the taxane to which they had been randomly assigned in the study.On the basis of multivariate analysis, significant prog-nostic indicators emerged for prolonged survival, TTP, and response for the ITT population. Predictors for OS included treatment with docetaxel (HR, 1.41; 95% CI, 1.15 to 1.73);KPS 80 ( P .005), less than 12 months from initial diagnosis to initial infusion (P .003), and fewer involved organs (P .01) 附上原文,方便翻譯者參考,此段在原文的5546頁 |

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我來試試,最后一段不是很確定。 在研究結(jié)束之后,64%用docetaxel治療的病人和70%用paclitaxel治療的病人(病人類型的指定在之前的研究中是隨機(jī)進(jìn)行的)繼續(xù)接受化學(xué)治療。 (下面這段是解釋如何進(jìn)行繼續(xù)化療的)在那些原先被隨機(jī)指定使用docetaxel的病人中,20%的人隨后使用paclitaxel治療,而在那些遠(yuǎn)些被隨機(jī)指定使用pacltiaxel的病人中,19%的人接受了docetaxel的補(bǔ)救性治療。13%原先使用docetaxel的病人和17%原先使用paclitaxel的病人繼續(xù)接受同一種紫杉烷類的藥物治療(即docetaxel的還用docetaxel,paclitaxel還用paclitaxel)。 根據(jù)多變量分析,在延長生存期、TTP(可能是血栓性血小板減少性紫癜)和對(duì)ITT(意圖性治療)的應(yīng)答上出現(xiàn)了顯著的預(yù)兆指標(biāo)。這些指標(biāo)包括使用docetaxel治療的整體存活率、從最初診斷到(infusion不知道怎么翻)少于12個(gè)月、更少的器官被癌細(xì)胞影響。 |
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