| 5 | 1/1 | 返回列表 |
| 查看: 1781 | 回復(fù): 4 | ||
[求助]
有沒有人知道detergent-resistant membranes 已有2人參與
|
| 細(xì)胞膜上有抗去垢劑區(qū)域嗎?detergent-resistant membranes,有沒有大神懂得給解釋一下,抗去垢劑膜和病毒內(nèi)吞有何聯(lián)系?因為一篇文章中說病毒的一些非結(jié)構(gòu)蛋白會和抗去垢劑膜相聯(lián)系,感謝。。。 |
|
History • 80’s Order (package) and disorder phases in diff. parts of the PM. • 90’s Analysis of membrane fractions by the use of mild detergents. The concept of Detergent Resistant Membranes (DRM) born. In this technique non-solubilized fraction of the PM extracts by mild detergent (triton X-100 at 4ºC –artifact conditions-) + sucrose gradient • 2000’s New microscopy techniques: FRET, STED, FRAP… To understand the dynamic of the assembly of sterol, sphingolipds and proteins in living cells (real conditions). Membrane domain definition: Lateral compartment (PM plane) with composition, structure and biological function diff. from the surrounding membrane. Regardless size, stability and mechanism of formation. Why DRMs/DIMs (detergent insoluble microdomains) are not lipid rafts??? • 4ºC is not a real condition for the behavior of the PM. • Quantitative bias due the ratio concentration of detergent:prot. /detergent:lipids Definition by consensus 2006: “Membrane rafts are small (10-200nm), heterogeneous highly dynamic, sterol and sphingolipid-enriched domains that compartmentalized cellular process” What is new here: No: detergent resistant, lipid term, or PM (E.g. membrane of mitochondria), small (need of superesolution techniques). |
新蟲 (初入文壇)
新蟲 (初入文壇)
| 5 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 一志愿南京理工大學(xué)085701資源與環(huán)境302分求調(diào)劑 +3 | 葵梓衛(wèi)隊 2026-03-18 | 5/250 |
|
|---|---|---|---|---|
|
[考研] 288求調(diào)劑,一志愿華南理工大學(xué)071005 +5 | ioodiiij 2026-03-17 | 5/250 |
|
|
[考研] 復(fù)試調(diào)劑 +4 | z1z2z3879 2026-03-14 | 6/300 |
|
|
[考研] 一志愿北京化工大學(xué)0703化學(xué)318分,有科研經(jīng)歷,求調(diào)劑 +3 | 一瓶苯甲酸 2026-03-14 | 3/150 |
|
|
[考研] 本人考085602 化學(xué)工程 專碩 +17 | 不知道叫什么! 2026-03-15 | 19/950 |
|
|
[考研] 材料與化工求調(diào)劑 +7 | 為學(xué)666 2026-03-16 | 7/350 |
|
|
[考研] 304求調(diào)劑 +3 | 曼殊2266 2026-03-18 | 3/150 |
|
|
[考研] 材料工程專碩調(diào)劑 +5 | 204818@lcx 2026-03-17 | 6/300 |
|
|
[考研] 085410人工智能專碩317求調(diào)劑(0854都可以) +3 | xbxudjdn 2026-03-18 | 3/150 |
|
|
[考研] 298-一志愿中國農(nóng)業(yè)大學(xué)-求調(diào)劑 +7 | 手機(jī)用戶 2026-03-17 | 7/350 |
|
|
[考研] 材料,紡織,生物(0856、0710),化學(xué)招生啦 +3 | Eember. 2026-03-17 | 9/450 |
|
|
[考研] 265求調(diào)劑 +3 | 梁梁校校 2026-03-17 | 3/150 |
|
|
[考研] 301求調(diào)劑 +9 | yy要上岸呀 2026-03-17 | 9/450 |
|
|
[考研] 301求調(diào)劑 +4 | A_JiXing 2026-03-16 | 4/200 |
|
|
[考研] [導(dǎo)師推薦]西南科技大學(xué)國防/材料導(dǎo)師推薦 +3 | 尖角小荷 2026-03-16 | 6/300 |
|
|
[考研] 0703一志愿211 285分求調(diào)劑 +5 | ly3471z 2026-03-13 | 5/250 |
|
|
[考研] 266求調(diào)劑 +4 | 學(xué)員97LZgn 2026-03-13 | 4/200 |
|
|
[考研] 0856材料與化工301求調(diào)劑 +5 | 奕束光 2026-03-13 | 5/250 |
|
|
[考研] 304求調(diào)劑 +7 | 7712b 2026-03-13 | 7/350 |
|
|
[考研] 295求調(diào)劑 +3 | 小匕仔汁 2026-03-12 | 3/150 |
|