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Malyhon新蟲(chóng) (小有名氣)
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[求助]
幾句論文求大神翻譯成中文 謝謝
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As for the RGD-modified film, the surface RGD peptides could be specifically recognized by integrin receptors on cell membranes, and thus cells could be anchored to the surface through a specific ligand-receptor binding. Therefore, the RGD-modified surface is more favorable to cells than the NH3 plasma-treated surface. Although the cell viability is similar on both surfaces, the cells with spindle-like morphology on the RGD-modified surface are in a better state than those on the NH3 plasma-treated surface, as shown in Figure 3b,d. The reason why the RGD-modified surface obtained by our modification procedure does not show a distinct advantage over the NH3 plasma-treated surface in terms of promoting cell proliferation is due to the existence of PEG chains, which could resist protein adsorption and cell adhesion. This partially screens the ability of RGD-modified surfaces for promoting cell adhesion and proliferation. |
金蟲(chóng) (著名寫手)
| 就RGD修飾膜而言,表面RGD縮氨酸可以通過(guò)細(xì)胞膜上整合素受體進(jìn)行特異性識(shí)別,從而細(xì)胞可以通過(guò)特定的配體-受體結(jié)合固定到該表面。 所以RGD修飾表面要比NH3表面對(duì)細(xì)胞更為有利。盡管細(xì)胞成活力在兩個(gè)表面上都是相似的,但是在RGD修飾的表面上的紡錘-狀細(xì)胞形態(tài)與那些在NH3等離子體處理過(guò)的表面上的相比較處于一個(gè)更好的狀態(tài),如圖3b,d所示。就促進(jìn)細(xì)胞增殖而言,之所以通過(guò)我們的修飾方法得到的RGD-修飾表面沒(méi)有顯示出比NH3等離子體處理過(guò)的表面具有明顯優(yōu)勢(shì),是由于PEG鏈的存在,這會(huì)抵抗蛋白質(zhì)吸附和細(xì)胞粘附。對(duì)RGD修飾的表面的能力進(jìn)行部分地篩選以促進(jìn)細(xì)胞粘附力和繁殖。 |
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