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Malyhon

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[求助] 幾句論文求大神翻譯成中文謝謝

As for the RGD-modified film, the surface RGD
peptides could be specifically recognized by integrin receptors
on cell membranes, and thus cells could be anchored to the
surface through a specific ligand-receptor binding. Therefore,
the RGD-modified surface is more favorable to cells than the
NH3 plasma-treated surface. Although the cell viability is similar
on both surfaces, the cells with spindle-like morphology on the
RGD-modified surface are in a better state than those on the
NH3 plasma-treated surface, as shown in Figure 3b,d. The reason
why the RGD-modified surface obtained by our modification
procedure does not show a distinct advantage over the NH3
plasma-treated surface in terms of promoting cell proliferation
is due to the existence of PEG chains, which could resist protein
adsorption and cell adhesion. This partially screens the ability
of RGD-modified surfaces for promoting cell adhesion and
proliferation.

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Malyhon: 金幣+9, ★★★★★最佳答案 2015-03-29 12:13:51

就RGD修飾膜而言,表面RGD縮氨酸可以通過細(xì)胞膜上整合素受體進(jìn)行特異性識別,從而細(xì)胞可以通過特定的配體-受體結(jié)合固定到該表面。所以RGD修飾表面要比NH3表面對細(xì)胞更為有利。盡管細(xì)胞成活力在兩個(gè)表面上都是相似的,但是在RGD修飾的表面上的紡錘-狀細(xì)胞形態(tài)與那些在NH3等離子體處理過的表面上的相比較處于一個(gè)更好的狀態(tài),如圖3b,d所示。就促進(jìn)細(xì)胞增殖而言，之所以通過我們的修飾方法得到的RGD-修飾表面沒有顯示出比NH3等離子體處理過的表面具有明顯優(yōu)勢，是由于PEG鏈的存在,這會(huì)抵抗蛋白質(zhì)吸附和細(xì)胞粘附。對RGD修飾的表面的能力進(jìn)行部分地篩選以促進(jìn)細(xì)胞粘附力和繁殖。

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2樓2015-03-29 08:43:22

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