版塊導(dǎo)航: 正在加載中...

應(yīng)《網(wǎng)絡(luò)安全法》要求，自2017年10月1日起，未進(jìn)行實(shí)名認(rèn)證將不得使用互聯(lián)網(wǎng)跟帖服務(wù)。為保障您的帳號(hào)能夠正常使用，請(qǐng)盡快對(duì)帳號(hào)進(jìn)行手機(jī)號(hào)驗(yàn)證，感謝您的理解與支持！

24小時(shí)熱門版塊排行榜

返回列表

IkaoIkao

新蟲 (小有名氣)

應(yīng)助: 0 (幼兒園)
金幣: 8
散金: 10
帖子: 60
在線: 21.5小時(shí)
蟲號(hào): 1494063
注冊(cè): 2011-11-16
專業(yè): 人類遺傳學(xué)

[求助] EI或ISTP檢索信息

回復(fù)此樓

» 猜你喜歡

293求調(diào)劑已經(jīng)有14人回復(fù)
0703化學(xué)336分求調(diào)劑已經(jīng)有6人回復(fù)
304求調(diào)劑已經(jīng)有9人回復(fù)
281求調(diào)劑（0805）已經(jīng)有8人回復(fù)
環(huán)境領(lǐng)域全國重點(diǎn)實(shí)驗(yàn)室招收博士1-2名已經(jīng)有3人回復(fù)
材料專碩306英一數(shù)二已經(jīng)有10人回復(fù)
301求調(diào)劑已經(jīng)有6人回復(fù)
一志愿天津大學(xué)化學(xué)工藝專業(yè)（081702）315分求調(diào)劑已經(jīng)有7人回復(fù)
302求調(diào)劑已經(jīng)有6人回復(fù)
26博士申請(qǐng) 已經(jīng)有3人回復(fù)

1樓 2015-12-04 16:50:59

已閱回復(fù)此樓關(guān)注TA 給TA發(fā)消息送TA紅花 TA的回帖

lazy錦溪

版主 (知名作家)

應(yīng)助: 155 (高中生)
貴賓: 2.371
金幣: 26118.4
散金: 15360
紅花: 180
沙發(fā): 15
帖子: 5537
在線: 1929.5小時(shí)
蟲號(hào): 2046157
注冊(cè): 2012-10-06
性別: GG
專業(yè): 功能與智能高分子
管轄: 檢索知識(shí)

【答案】應(yīng)助回帖

★ ★ ★ ★ ★
IkaoIkao: 金幣+5, ★★★★★最佳答案, 非常感謝！ 2015-12-10 00:18:03

Analysis of a Haplotype Structure in a Non-coding Region of Human Chromosome 22

作者:Jian-hong Sun

2015 Seventh International Conference on Measuring Technology and Mechatronics Automation (ICMTMA)

頁: 137-40

DOI: 10.1109/ICMTMA.2015.39

出版年: 2015

會(huì)議名稱

會(huì)議:2015 Seventh International Conference on Measuring Technology and Mechatronics Automation (ICMTMA)

會(huì)議地點(diǎn):Nanchang, China

會(huì)議日期:13-14 June 2015

會(huì)議贊助商:Hunan Inst. Ind.
摘要

Haplotype structures are important in the study of human evolutionary history. These structures effectively simplify genome-wide association studies by reducing the number of mutations to be examined. Here, a haplotype block was analysed which located on 22q12.3 (Position: 34876961-34890077), a noncoding region of chromosome 22. Statistical tests suggested that the region is selectively neutral with a very low recombination rate. The genetic diversity analysis shows that the African population (AFR) has higher diversity than non-AFR populations. The results show that only 52 of 2,184 possible haplotypes are observed on this block. The haplotype distribution concentrates on 4~5 common haplotypes in non-African populations. However, the haplotypes are more evenly and more widely expressed in AFR. Due to genetic drift or sampling, these SNPs with strong LD(Linkage Disequilibrium) of this block is not observed in ASN. Results show that the strong LD structure was generated before humans left Africa.
作者信息

作者地址: Jian-hong Sun; Eng. Coll., Honghe Univ., Mengzi, China.
出版商

IEEE Computer Society, Los Alamitos, CA, USA
類別 / 分類

研究方向:Cell Biology; Mathematics (由 Thomson Reuters 提供)

分類代碼:A8725F Physics of subcellular structures; A0250 Probability theory, stochastic processes, and statistics

受控索引:cellular biophysics; genetics; statistical testing

非受控索引:haplotype structure; noncoding region; human chromosome 22; human evolutionary history; genome-wide association; haplotype block; statistical tests; recombination rate; genetic diversity analysis; African population; nonAfrican populations; linkage disequilibrium
文獻(xiàn)信息

文獻(xiàn)類型:Conference Paper

語種:English

入藏號(hào):INSPEC:15455675

ISBN:978-1-4673-7143-8

參考文獻(xiàn)數(shù):17
其他信息

處理類型:Experimental

U.S. Copyright Clearance Center 代碼:978-1-4673-7143-8/15/$31.00

回復(fù)此樓

2樓2015-12-08 19:20:29