| 5 | 1/1 | 返回列表 |
| 查看: 1396 | 回復: 8 | |||
| 當前只顯示滿足指定條件的回帖,點擊這里查看本話題的所有回帖 | |||
[求助]
求救Rosetta dock!!!小弟銀兩有限,跪謝!
|
|||
|
各位蟲友! 我在Rosetta上提交ligand-reception.pdb, 官網(wǎng)提示:Not enough chains in submitted protein! [At least two chains should be present] Invalid docking partners string, must be list of chains in correct order, without repetion separated by underscore! 請問用Surflexdock怎么解決這個問題 。?如何把結合上的配體也命名成一條 鏈??萬分感謝各位了。! 官網(wǎng)tutorial說了這么幾句話,費解。 1、when creating a combined single input file with both partners, place a TER linebetween the two paners. RosettaDock is that protein backbone 2、conformations typically do not change much upon association. This holds for many proteins, but not all. If you believe that the backbone of one of your partners is flexible, you should be cautious with the results. docking of a short, flexible peptide (~10 residues) is not likely to work, since a peptide lacks the tertiary interactions which stabilize full-size domains (75-250 residues). 看了半天也不知在pdb哪里加TER,而且配 體恰好就是7個aa,會不會backbone conformation改變。繉嵲诒父魑淮 俠,不是學藥化的傷不起。! [ 發(fā)自手機版 http://www.gaoyang168.com/3g ] |
酶的資料 |
送鮮花一朵 |
謝謝!敢問下前輩:我用的是Rosetta 網(wǎng)頁版,http://rosettaserver.graylab.jhu.edu/docking/submit是不是必須裝Rosetta才能進Rosetta flexpep模塊?謝謝前輩~。! |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 085701環(huán)境工程求調劑 +8 | 多久上課 2026-03-27 | 8/400 |
|
|---|---|---|---|---|
|
[考研] 張芳銘-中國農業(yè)大學-環(huán)境工程專碩-298 +3 | 手機用戶 2026-03-26 | 3/150 |
|
|
[考研] 086000調劑 +3 | 7901117076 2026-03-26 | 3/150 |
|
|
[考研] 一志愿上海理工能源動力(085800)310分求調劑 +3 | zhangmingc 2026-03-27 | 4/200 |
|
|
[考研] 307求調劑 +8 | 超級伊昂大王 2026-03-24 | 9/450 |
|
|
[考研] 308求調劑 +6 | 墨墨漠 2026-03-27 | 6/300 |
|
|
[材料工程] 一志愿C9材料與化工專業(yè)總分300求調劑 +7 | 曼111 2026-03-24 | 8/400 |
|
|
[考研] 0856材料化工調劑 總分330 +8 | zhubinhao 2026-03-27 | 8/400 |
|
|
[考研] 085600材料與化工306 +10 | z1z2z3879 2026-03-21 | 11/550 |
|
|
[考研] 324求調劑 +5 | hanamiko 2026-03-26 | 5/250 |
|
|
[考研] 329求調劑 +7 | 鈕恩雪 2026-03-25 | 7/350 |
|
|
[考研] 調劑 +4 | 柚柚yoyo 2026-03-26 | 4/200 |
|
|
[考研] 289求調劑 +17 | 碩星赴 2026-03-23 | 17/850 |
|
|
[考研] 281求調劑 +6 | Koxui 2026-03-24 | 7/350 |
|
|
[考研] 材料277求調劑 +5 | min3 2026-03-24 | 5/250 |
|
|
[考研] 求b區(qū)院校調劑 +4 | 周56 2026-03-24 | 5/250 |
|
|
[考研] 各位老師您好:本人初試372分 +5 | jj涌77 2026-03-25 | 6/300 |
|
|
[考研]
|
13659058978 2026-03-24 | 4/200 |
|
|
[考研] 070300,一志愿北航320求調劑 +3 | Jerry0216 2026-03-22 | 5/250 |
|
|
[考研] 考研調劑 +3 | 呼呼?~+123456 2026-03-21 | 3/150 |
|