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yunyun89623金蟲 (小有名氣)
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[求助]
求助準(zhǔn)確的翻譯兩句話~~~謝謝啦
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| One characteristic of polymeric nanocarriers of particular importance in the field of pulmonary delivery is the fact that they have appropriate sizes to avoid macrophage clearance in the alveolar region, and may in principle be designed to control the delivery of the therapeutic of interest by either promoting transepithelial transport , or be transported itself (for systemic delivery) , via translocation or transcytosis , or to improve the retention of the API in the lungs in case the target is the lungs (regional delivery). |

鐵桿木蟲 (著名寫手)
Farmer
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One characteristic of polymeric nanocarriers of particular importance in the field of pulmonary delivery is the fact that they have appropriate sizes to avoid macrophage clearance in the alveolar region, and may in principle be designed to control the delivery of the therapeutic of interest by either promoting transepithelial transport , or ( the therapeutic of interest) be transported itself (for systemic delivery) , via translocation or transcytosis , or to improve the retention of the API in the lungs in case the target is the lungs (regional delivery). 聚合納米載體在肺部給藥領(lǐng)域一個(gè)尤其重要的特性是,事實(shí)上它們具有合適的粒徑,(因此)可以防止被肺泡區(qū)域內(nèi)的巨噬細(xì)胞(吞噬)清除,而且原則上,它們(聚合納米載體)可以被設(shè)計(jì)成: 1) 通過提高上皮輸運(yùn)能力可控輸運(yùn)所感興趣的治療藥物,2) 通過易位轉(zhuǎn)運(yùn)或胞吞轉(zhuǎn)運(yùn)作用自行輸送治療藥物(系統(tǒng)性輸運(yùn)), 3) 在靶向目標(biāo)為肺時(shí), 延長(zhǎng)API在肺部的停留時(shí)間。 P.S.: 現(xiàn)在隨著環(huán)境的污染,靶向藥物治療肺癌是一個(gè)很重要的肺癌治療手段。樓上加油,根治肺癌靠你了。 |

鐵桿木蟲 (正式寫手)
obscure nacissus
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FYR 聚合納米載體在肺部給藥領(lǐng)域有十分重要的作用,它的特性在于其具有合適的粒徑以防止自身在肺泡內(nèi)被巨噬細(xì)胞清除,而且設(shè)計(jì)它可能主要有兩方面的目的,其一:通過提高上皮轉(zhuǎn)運(yùn)能力——否則經(jīng)疏導(dǎo)作用將自身轉(zhuǎn)運(yùn)(進(jìn)行全身給藥)——或轉(zhuǎn)胞吞作用,控制有用藥物的傳遞;其二:在靶器官是肺時(shí)(局部給藥)提高APIs的保留。 |

金蟲 (小有名氣)

金蟲 (小有名氣)

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