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zjlizijian新蟲 (小有名氣)
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[求助]
中譯英，有空的幫下忙
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| 惡性腫瘤是危害人類健康和生命的重大疾病，近幾十年來，抗腫瘤新藥研發(fā)已經(jīng)取得了顯著成功。在抗腫瘤藥物的研發(fā)中，以生物靶分子為基礎(chǔ)進(jìn)行抗腫瘤藥物先導(dǎo)化合物的篩選是抗腫瘤藥物的研究熱點(diǎn)之一。DNA G-四鏈體結(jié)構(gòu)的發(fā)現(xiàn)及現(xiàn)代分子生物學(xué)技術(shù)對(duì)其生理功能的揭示，為目前抗腫瘤藥物研發(fā)提供了一個(gè)新的契機(jī)。能夠誘導(dǎo)DNA形成G-四鏈體結(jié)構(gòu)或者與G-四鏈體特異性結(jié)合，并使之穩(wěn)定的化合物有望抑制腫瘤細(xì)胞的生長(zhǎng)，從而達(dá)到抗癌的作用。因此，以G-四鏈體為靶點(diǎn)的抗腫瘤藥物的研究引起了人們的廣泛關(guān)注。 |
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yili_90
金蟲 (正式寫手)
- 翻譯EPI: 17
- 應(yīng)助: 37 (小學(xué)生)
- 貴賓: 0.013
- 金幣: 3136.5
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- 蟲號(hào): 2157293
- 注冊(cè): 2012-11-30
- 性別: MM
- 專業(yè): 動(dòng)物遺傳學(xué)
【答案】應(yīng)助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★
真強(qiáng)必勝: 金幣+1, 謝謝 2014-01-08 21:41:26
zjlizijian(phu_grassman代發(fā)): 金幣+8, good job. 2014-01-09 16:39:30
真強(qiáng)必勝: 金幣+1, 謝謝 2014-01-08 21:41:26
zjlizijian(phu_grassman代發(fā)): 金幣+8, good job. 2014-01-09 16:39:30
| Malignant tumor is a major disease which jeopardize health and life. Fortunately, new drug research of antineoplastic has made remarkable progress in recent decades. One of the hotpots in antineoplastic drugs research is to filter lead compounds of antineoplastic drugs via the basis like bio-target molecule. Discovering the structure of DNA G-quadruplex and revealing its physical function via modern molecular biology technique provide a new moment for antineoplastic drugs research. And stable compounds which is obtained by Inducing DNA to form G-quadruplex or bind to G-quadruplex specifically might can inhibit the growth of tumor cells and then play a anti-cancer rule. Thus, the method in which regard G-quadruplex as target has aroused much concern in the field of antineoplastic drugs research. |
3樓2013-10-07 13:15:30
hobbit2005
金蟲 (小有名氣)
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- 專業(yè): 天然有機(jī)化學(xué)
【答案】應(yīng)助回帖
★ ★ ★ ★ ★ ★ ★
zjlizijian(phu_grassman代發(fā)): 金幣+7, thanks 2014-01-09 16:39:38
zjlizijian(phu_grassman代發(fā)): 金幣+7, thanks 2014-01-09 16:39:38
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Cancer has been considered to be on of the most serious disease threatening health and life of human beings. The development of new anti-cancer drugs has made remarkable progress in recent decades, among which one of the most focused method is the screening of the precursor compound based on the bio-target molecules. The discovery of DNA G-四連體 structure and the reveal of its biological function via modern molecular biological technology have supplied a new opportunity in the development of anti-cancer drugs. The ability of compound that can induce and stablize DNA to form G-四連體 structure or to combine with its specific characterization would finally realize the function of anti-cancer. Thus, the research of the G-四連體 target molecule based anti-cancer drugs have been arousing wide concerns recently. PS. 四連體自己翻譯一下吧。 |
2樓2013-10-07 10:29:09
yili_90
金蟲 (正式寫手)
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4樓2013-10-07 13:17:06
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