 |
 |
 |
| 24小時(shí)熱門(mén)版塊排行榜 |
- >論壇更新日志 (4738)
- >考研 (937)
- >導(dǎo)師招生 (925)
- >文獻(xiàn)求助 (245)
- >休閑灌水 (105)
- >考博 (97)
- >蟲(chóng)友互識(shí) (95)
- >碩博家園 (75)
- >招聘信息布告欄 (70)
- >論文道賀祈福 (55)
- >基金申請(qǐng) (38)
- >博后之家 (31)
- >SciFinder/Reaxys (26)
- >論文投稿 (24)
- >綠色求助(高懸賞) (19)
- >找工作 (16)
 |
 |
 |
||
 |
 |
 |
 |
 |
| 2 | 1/1 | 返回列表 |
| 查看: 777 | 回復(fù): 1 | |||
qiuqinglei5020
|
[求助]
阿哌沙班液相分析條件？
|
| 有做阿哌沙班的嗎？液相條件幫忙說(shuō)一下 |
回復(fù)此樓» 收錄本帖的淘帖專(zhuān)輯推薦
 新藥研發(fā)注冊(cè)申報(bào) |
» 猜你喜歡
2026申博推薦
已經(jīng)有1人回復(fù)
-
一篇擴(kuò)散模型的Nature Machine Intelligence論文和Elsevier上的深度學(xué)習(xí)藥物書(shū)籍
已經(jīng)有1人回復(fù)
-
藥物學(xué)論文潤(rùn)色/翻譯怎么收費(fèi)?
已經(jīng)有280人回復(fù)
-
中國(guó)藥科大學(xué)2026入學(xué)博士，藥物合成和設(shè)計(jì)經(jīng)驗(yàn)，放射化學(xué)及放射醫(yī)學(xué)研究
已經(jīng)有25人回復(fù)
-
使用MolAICal進(jìn)行多肽虛擬篩選教程-同樣適用于蛋白質(zhì)和核酸的虛擬篩選
已經(jīng)有1人回復(fù)
-
使用MolAICal計(jì)算藥物化學(xué)過(guò)濾器MCFs及MCE-18描述符
已經(jīng)有0人回復(fù)
-
使用MolAICal發(fā)現(xiàn)蛋白受體潛在的活性口袋及位點(diǎn)
已經(jīng)有0人回復(fù)
-
華理藥學(xué)學(xué)碩求調(diào)劑，總分324
已經(jīng)有0人回復(fù)
-
廣西醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院自身免疫病課題組招收基礎(chǔ)醫(yī)學(xué)相關(guān)專(zhuān)業(yè)的調(diào)劑研究生
已經(jīng)有2人回復(fù)
-
澳門(mén)理工大學(xué)人工智能藥物發(fā)現(xiàn)中心招收2026級(jí)博士研究生（申請(qǐng)-考核制）
已經(jīng)有10人回復(fù)
» 本主題相關(guān)價(jià)值貼推薦，對(duì)您同樣有幫助:
- 島津液相色譜一臺(tái)，如何對(duì)儀器和分析條件進(jìn)行設(shè)置，使峰面積增大？？
已經(jīng)有11人回復(fù)
- 液相色譜測(cè)定苯酚的濃度的條件及柱子類(lèi)型
已經(jīng)有12人回復(fù)
- 【求助】關(guān)于有機(jī)鹽類(lèi)農(nóng)藥的液相檢測(cè)時(shí)液相色譜柱選擇及其色譜條件
已經(jīng)有8人回復(fù)
- 液相色譜的安裝條件要求，特別是環(huán)境要求
已經(jīng)有5人回復(fù)
- 液相色譜分離條件的優(yōu)化
已經(jīng)有9人回復(fù)
- 苯酐（鄰苯二甲酸酐）液相分析的條件�。�！
已經(jīng)有14人回復(fù)
- 胡蘿卜素液相條件：安捷倫1260反相C18色譜柱
已經(jīng)有14人回復(fù)
- 求助：五氯酚鈉的高效液相色譜的條件？
已經(jīng)有6人回復(fù)
- 樣品檢測(cè) 不知道液相條件怎么選擇？？謝謝�。。�
已經(jīng)有5人回復(fù)
- 【求助】液相色譜色譜條件選擇問(wèn)題，謝謝！
已經(jīng)有3人回復(fù)
- 【求助】求助：在ESI離子源條件下，液相流動(dòng)相的配制應(yīng)注意哪些問(wèn)題?
已經(jīng)有8人回復(fù)
- 【求助】液相分離條件篩選出來(lái)后，進(jìn)行質(zhì)譜分析，質(zhì)譜響應(yīng)程度的影響因素有哪些呢？
已經(jīng)有5人回復(fù)
- 【求助】液質(zhì)聯(lián)用分析中對(duì)液相色譜條件的流動(dòng)相有什么具體的要求？
已經(jīng)有4人回復(fù)
yanghuping
木蟲(chóng) (正式寫(xiě)手)
- 應(yīng)助: 100 (初中生)
- 金幣: 5118.5
- 散金: 2331
- 紅花: 8
- 沙發(fā): 1
- 帖子: 939
- 在線: 1099.7小時(shí)
- 蟲(chóng)號(hào): 965040
- 注冊(cè): 2010-03-08
- 性別: GG
- 專(zhuān)業(yè): 有機(jī)合成
【答案】應(yīng)助回帖
感謝參與，應(yīng)助指數(shù) +1
|
有一篇文獻(xiàn)上面的分析條件：General Experimental: All reagents used were of ACS grade or higher. Flash chromatography was performed using either a Biotage Flash Chromatography System or an AnaLogix BSR Solvent Pump System with silica gel cartridges. HPLC analyses for the syntheses were performed on an Agilent 1100 HPLC system including solvent degasser, pump, automated injector and variable UV detector connected to either an IN/US BetaRam Flow Detector with a 0.25ml detector cell or a Berthold Scintillation Detector with a 0.5 ml detector cell. HPLC gradient 1 = Phenomenex Luna C18, 5 mm, 4.6150mm column. Mobile phase A = 0.05% TFA in water, mobile phase B = 0.05% TFA in acetonitrile, 0min 95% A, 6min 50% A, 11 min 95% B, 13 min 95% B, 15 min 95% A, UV detection at 254 nm. HPLC gradient 2 = Vydac protein and peptide C18, 4.6250mm column. Mobile phase A= 0.05% TFA in water, mobile phase B = 0.05% TFA in acetonitrile, 0min 90% A, 16 min 90% B, 23 min 95% B, 25 min 90% A, UV detection at 254 nm. HPLC Gradient 3 = Phenomenex, Luna, C18 (2), 3 mm, 1504.6mm column with Brownlee, RP-18 C18, 3 mm, 153.2mm guard column, column temperature = 301C, autosampler temperature = 41C, mobile phase A = 0.4% formic acid in water adjusted to pH 3.2 with NH4OH, mobile phase B = acetonitrile, mobile phase C = MeOH, 0 min 100% A, 25 min 20% A and 80% B, 27min 50% B and 50% C, 32 min 50% B and 50% C, 34 min 100% A, flowrate = 1.0ml/min at 323 nm. HPLC Gradient 4 =Ace 3, C18, 3 mm, 1504.6mm column with Ace 3, C18, 3 mm, 103.0mm guard column, column temperature = 351C, autosampler temperature = ambient, mobile phase A = 0.4% formic acid in water, adjusted to pH 3.2 with NH4OH, mobile phase B = acetonitrile, 0min 100% A, 3min 100% A, 5min 90% A, 20 min 75% A, 50 min 75% A, 60 min 50% A, 65 min 100% B, 70 min 100% B, 72 min 100% A, flowrate = 0.7ml/min, UV detection at 240 nm. Preparative HPLC condition 1: Phenomenex Luna 5 mm, 25021.2mm column. Mobile phase A = 0.1% TFA in water, mobile phase B = 0.1% TFA in acetonitrile, 0 min 70% A, 18 min 95% B, 22 min 95% B, 25 min 70% A, flowrate = 15 ml/min. UV detection at 254 nm. Preparative HPLC condition 2: Zorbax SB-C18 5 mm, 25021.2mm column. Mobile phase A = 0.05% TFA in water, mobile phase B = 0.05% TFA in acetonitrile, 0 min 90% A, 16 min 90% B, 23 min 95% B, 25 min 90% A, Flowrate = 9.9ml/min, UV detection at 254 nm. LC/MS analysis was performed on a Finnigan LXQ Mass Spectrometer System. NMR spectra were recorded on a Bruker AVANCE II 300MHz Spectrometer with an UltrashieldTM Magnet or a Varian Unity/Inova 300MHz Spectrometer. Specific activities were performed gravimetrically. Liquid scintillation counting was performed on either a PerkinElmer Tri-Carb Model 2900Tr or a Wallac Model 1409 Liquid Scintillation Counter. |
» 本帖附件資源列表
-
歡迎監(jiān)督和反饋：小木蟲(chóng)僅提供交流平臺(tái)，不對(duì)該內(nèi)容負(fù)責(zé)。
本內(nèi)容由用戶(hù)自主發(fā)布，如果其內(nèi)容涉及到知識(shí)產(chǎn)權(quán)問(wèn)題，其責(zé)任在于用戶(hù)本人，如對(duì)版權(quán)有異議，請(qǐng)聯(lián)系郵箱：xiaomuchong@tal.com - 附件 1 : 1890_ftp.pdf
2013-10-17 15:46:21, 998.45 K
2樓2013-10-17 15:43:13
相關(guān)版塊跳轉(zhuǎn)
我要訂閱樓主 wshj1234 的主題更新
| 2 | 1/1 | 返回列表 |
| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
