| 查看: 2714 | 回復(fù): 12 | ||
| 本帖產(chǎn)生 1 個(gè) SFL-EPI ,點(diǎn)擊這里進(jìn)行查看 | ||
347416682金蟲(chóng) (小有名氣)
|
[求助]
求助中文摘要翻譯成英文。。。 已有3人參與
|
|
| 本人英語(yǔ)水平太差,實(shí)在翻譯不了。 求助各位英語(yǔ)大神。。。。 |
木蟲(chóng) (正式寫(xiě)手)

木蟲(chóng) (正式寫(xiě)手)
|
In the late 1960s,Cisplatin was found has curative effect to a variety of cancers.Soon afters,plenty of Platinum derivatives were synthesized constantly.However,it's necessary to exploit new kinds of cisplatin anti-cancer drug because of its strong toxic and side effects.Steroids is a type of native compound with physiological activity,which is widely existed in creature having biological activity to various cancer cells.If combine sterides with metal effect groups,it may create a better result of suppressing tumor growth. Based on researches on steroidal compounds against tumor and metal complexes may have antitumor activity previously.This paper designed synthesis 23 new steroidal metal complexes and test biological activity on some of them.Four 3 - any thiourea steroidal metal complexes,nine 20 - ammonia thiourea steroidal metal complexes and ten 17 - ammonia thiourea steroidal metal complexes included and measure some compouds on antitumor activity in vitro. 樓主這是前兩段,請(qǐng)查收! |

木蟲(chóng) (正式寫(xiě)手)
|
1.Synthesising 20 - ammonia thiourea steroidal metal complexes.Puting changed pregnenolone third-substituent react with thiosemicarbazone with different substituents.And then,reacting with K2PtCl4,CuCl2·2H2O,[Ru(η6-p-cymene)Cl2]2,from which we can get 8 kinds of metallic 20 - ammonia thiourea class steroid complexes.Reacting oestrone with 2 - hydrazine base pyridine,then reacting with CuCl2·2H2O,gaining 20 - hydrazine (2 -) pyridine steroidal metal complexes.We can discover that some compounds show good activity of inhibiting tumor cell proliferation from antitumor activity in vitro experiment.Such as compoud 4 and compoud 9,their IC50 figure to HELA cell is 9.5μmol/L and 4.8μmol/L. 第三段 |

捐助貴賓 (著名寫(xiě)手)
|
您好: 以下是我給您翻譯的第一段, 因?yàn)樘由蠈?zhuān)業(yè)術(shù)語(yǔ)也需要查閱, 所以只翻譯了一段, 如果有用就采納吧。 “In the late 1960s, cis-platinum (cisplatin) was found to have certain curative effect on a variety of cancers. Later, plenty of Platinum derivatives were continuously synthesized. However, owing to the strong toxicity of cis-platinum, such as the adverse effect of causing severe nausea, neurotoxicity, myelosuppression etc., it is very necessary to develop new kinds of anti-cancer platinum. Steroid, widely found in animals and plants, is a type of natural compound with a wide range of physiological activities. Besides, steroid inhibited various cancer cells. Therefore, it is hypothesized that combination of steroid with effective groups of metals might show greater inhibitory effects on tumor growth.” |

捐助貴賓 (著名寫(xiě)手)

捐助貴賓 (著名寫(xiě)手)
|
這是第二段的翻譯, 供您參考。 "Based on our previous researches on anti- tumor steroidal compounds and potential anti- tumor metal complexes, 23 new steroidal metal complexes were designed and synthesized, including four 3-thiosemicarbazone steroid metal complexes, nine 20 - thiosemicarbazone steroid metal complexes and ten 17 - thiosemicarbazone steroid metal complexes. The biological activities of the 23 complexes were tested and their in-vitro anti-tumor efficacy assay was also performed. " |

捐助貴賓 (著名寫(xiě)手)
|
這是第三段的翻譯, 供您參考。 "Synthesis of 20 - thiosemicarbazone steroid metal complexes: the third-substituent of pregnenolone was changed before it reacted with thiosemicarbazone with different substituents. Then, it reacted respectively with K2PtCl4, CuCl2•2H2O and [Ru(η6-p-cymene)Cl2]2, producing 8 different 20 - thiosemicarbazone steroid metal complexes; pregnenolone was also put to reacted with 2-hydrazono-pyridine before it reacted with CuCl2•2H2O, generating 20 - hydrazine (2 -) pyridine steroidal metal complexes. In-vitro anti-tumor experiments indicated that some of the synthesized compounds showed comparatively strong inhibitory effects on the proliferation of tumor cells, with IC50 of compound 4 and 9 to HELA cell being 9.5 and 4.8μmol/L respectively. " |

|
本帖內(nèi)容被屏蔽 |
木蟲(chóng) (正式寫(xiě)手)

| 最具人氣熱帖推薦 [查看全部] | 作者 | 回/看 | 最后發(fā)表 | |
|---|---|---|---|---|
|
[考研] 299求調(diào)劑 +4 | shxchem 2026-03-20 | 6/300 |
|
|---|---|---|---|---|
|
[考研] 286分人工智能專(zhuān)業(yè)請(qǐng)求調(diào)劑愿意跨考! +3 | lemonzzn 2026-03-17 | 5/250 |
|
|
[考研] 085601調(diào)劑 358分 +3 | zzzzggh 2026-03-20 | 4/200 |
|
|
[考研] 機(jī)械專(zhuān)碩299求調(diào)劑至材料 +3 | kkcoco25 2026-03-16 | 4/200 |
|
|
[考研] 278求調(diào)劑 +6 | 煙火先于春 2026-03-17 | 6/300 |
|
|
[考研] 324求調(diào)劑 +5 | lucky呀呀呀鴨 2026-03-20 | 5/250 |
|
|
[考研]
|
然11 2026-03-19 | 4/200 |
|
|
[考研] 藥學(xué)383 求調(diào)劑 +3 | 藥學(xué)chy 2026-03-15 | 5/250 |
|
|
[考研] 北科281學(xué)碩材料求調(diào)劑 +5 | tcxiaoxx 2026-03-20 | 5/250 |
|
|
[考研] 求調(diào)劑一志愿南京航空航天大學(xué)289分 +3 | @taotao 2026-03-19 | 3/150 |
|
|
[考研] 一志愿西南交通 專(zhuān)碩 材料355 本科雙非 求調(diào)劑 +5 | 西南交通專(zhuān)材355 2026-03-19 | 5/250 |
|
|
[考研] 一志愿華中農(nóng)業(yè)071010,總分320求調(diào)劑 +3 | 困困困困坤坤 2026-03-20 | 3/150 |
|
|
[考研] 261求B區(qū)調(diào)劑,科研經(jīng)歷豐富 +3 | 牛奶很忙 2026-03-20 | 4/200 |
|
|
[考研] 材料學(xué)碩318求調(diào)劑 +5 | February_Feb 2026-03-19 | 5/250 |
|
|
[考研] 本科鄭州大學(xué)物理學(xué)院,一志愿華科070200學(xué)碩,346求調(diào)劑 +4 | 我不是一根蔥 2026-03-18 | 4/200 |
|
|
[考研] 材料工程專(zhuān)碩調(diào)劑 +5 | 204818@lcx 2026-03-17 | 6/300 |
|
|
[考研]
|
胡辣湯放糖 2026-03-15 | 6/300 |
|
|
[考研] 材料,紡織,生物(0856、0710),化學(xué)招生啦 +3 | Eember. 2026-03-17 | 9/450 |
|
|
[考研] 304求調(diào)劑 +3 | 曼殊2266 2026-03-14 | 3/150 |
|
|
[考研] 327求調(diào)劑 +6 | 拾光任染 2026-03-15 | 11/550 |
|